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Date of Award
5-2026
Document Type
Restricted Thesis: Campus only access
Degree Name
Master of Science in Biology
Department
Biology
First Reader/Committee Chair
Nicole Bournias-Vardiabasis
Abstract
The development of biodegradable alloys has progressed over several decades and continues to show significant promise in the biomedical field. In this study, we examine zinc-based alloys and their behavior when exposed to environments that mimic human physiological conditions. By immersing these alloys in solutions such as revised simulated body fluid (r-SBF) and Dulbecco’s Modified Eagle Medium (DMEM), we evaluate their degradation characteristics and biocompatibility. With the goal of identifying materials that safely dissolve in the body with minimal toxicity while promoting stem cell activity, we investigate zinc alloys containing various trace elements under controlled, in vitro conditions. This study incorporates both corrosion/degradation testing and cell experiments to provide a comprehensive understanding of how these alloys behave electrochemically and biologically within a simulated mammalian environment.
Recommended Citation
Silva Barcenas, Mayra D., "IN VITRO STUDIES ON DEGRADATION OF BIO ALLOYS AND CYTOCOMPATIBILITY WITH BONE MARROW DERIVED STEM CELLS" (2026). Electronic Theses, Projects, and Dissertations. 2437.
https://scholarworks.lib.csusb.edu/etd/2437