Date of Award

2013

Document Type

Thesis

Degree Name

Master of Science in Biology

Department

Biology

First Advisor

Chao, Michael

Second Advisor

Bournias-Vardiabasis, Nicole

Third Advisor

Orwin, Paul

Abstract

This study investigates how DA (dopamine) modulates GLU (glutamate) signaling at the interneuron level of the C. elegans avoidance circuit in response to the noxious chemical 1-octanol. Many neural processes involved in addiction, exhibit cellular mechanisms using the neurotransmitters dopamine and glutamate along with their intracellular and genomic targets.

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