Event Title

Developing Chemical Tools to Probe Malarial Protease Biology

Presenter Information

Ruby Aispuro

Presentation Type

Poster Presentation/Art Exihibt

College

College of Natural Sciences

Major

Chemistry and Biochemistry

Location

Event Center A & B

Faculty Mentor

Dr. Jeremy Mallari

Start Date

5-19-2016 1:00 PM

End Date

5-19-2016 2:30 PM

Abstract

The goal of the research is to develop chemical inhibitors that selectively block specific metalloproteases. We will be doing this by developing an activity assay (which we are currently doing now), design, synthesize and test inhibitors against metalloproteases, target inhibitors in P. Falciparum, and analyze phenotypes. We are currently making assay in order to start testing them and seeing which assay work best.

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May 19th, 1:00 PM May 19th, 2:30 PM

Developing Chemical Tools to Probe Malarial Protease Biology

Event Center A & B

The goal of the research is to develop chemical inhibitors that selectively block specific metalloproteases. We will be doing this by developing an activity assay (which we are currently doing now), design, synthesize and test inhibitors against metalloproteases, target inhibitors in P. Falciparum, and analyze phenotypes. We are currently making assay in order to start testing them and seeing which assay work best.