Event Title

Characterization of Two Influenza Nucleoprotein Body Domain Mutants

Presenter Information

Anita Sahagian

Presentation Type

Poster Presentation

College

College of Natural Sciences

Major

Biology

Location

Event Center B

Faculty Mentor

Dr. Laura Newcomb

Start Date

2-27-2013 10:10 AM

End Date

2-27-2013 6:00 PM

Abstract

The purpose of this study is to characterize an NP mutant, Npbd3, designed to disrupt interaction with viral RdRP. NPbd3 is defective for viral mRNA transcription and viral RNA replication. We aim to identify any NP interaction that are altered in the presence of NPbd3 in order to identify potential antiviral targets.

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Feb 27th, 10:10 AM Feb 27th, 6:00 PM

Characterization of Two Influenza Nucleoprotein Body Domain Mutants

Event Center B

The purpose of this study is to characterize an NP mutant, Npbd3, designed to disrupt interaction with viral RdRP. NPbd3 is defective for viral mRNA transcription and viral RNA replication. We aim to identify any NP interaction that are altered in the presence of NPbd3 in order to identify potential antiviral targets.