Paradoxical behavior effects of dopamine receptor inactivation in preweanling rats: Role of the dorsal striatum
Date of Award
Master of Science in Psychology
McDougall, Sanders A.
Crawford, Cynthia A.
The purpose of this thesis was to: a) investigate the effects of intrastriatally administered N-ethoxycarbonyl-2ethoxy-1, 2-dihydroquinoline (EEDQ) on nonselective dopamine agonists (NPA) -induced locomotor activity in preweanling and adult rats; b) determine which dopamine receptor subtype (D1- or D2-like) is responsible for modulating EEDQ's paradoxical behavioral effects in preweanling rats; and c) examine the magnitude of EEDQ-induced D1- and D2-like receptor inactivation in both adult and preweanling rats. Subjects were 252 male and female rat pups of Sprague-Dawley descent (Charles River Laboratories, Hollister, CA, USA), born and raised at California State University, San Bernardino (CSUSB).
Der-Ghazarian, Taleen Siran, "Paradoxical behavior effects of dopamine receptor inactivation in preweanling rats: Role of the dorsal striatum" (2012). Theses Digitization Project. 4135.