Date of Award
2012
Document Type
Thesis
Degree Name
Master of Science in Psychology
Department
Psychology
First Advisor
McDougall, Sanders A.
Second Advisor
Crawford, Cynthia A.
Third Advisor
Zavala, Arturo
Abstract
The purpose of this thesis was to: a) investigate the effects of intrastriatally administered N-ethoxycarbonyl-2ethoxy-1, 2-dihydroquinoline (EEDQ) on nonselective dopamine agonists (NPA) -induced locomotor activity in preweanling and adult rats; b) determine which dopamine receptor subtype (D1- or D2-like) is responsible for modulating EEDQ's paradoxical behavioral effects in preweanling rats; and c) examine the magnitude of EEDQ-induced D1- and D2-like receptor inactivation in both adult and preweanling rats. Subjects were 252 male and female rat pups of Sprague-Dawley descent (Charles River Laboratories, Hollister, CA, USA), born and raised at California State University, San Bernardino (CSUSB).
Recommended Citation
Der-Ghazarian, Taleen Siran, "Paradoxical behavior effects of dopamine receptor inactivation in preweanling rats: Role of the dorsal striatum" (2012). Theses Digitization Project. 4135.
https://scholarworks.lib.csusb.edu/etd-project/4135
