Date of Award
2013
Document Type
Thesis
Degree Name
Master of Science in Biology
Department
Biology
First Advisor
Newcomb, Laura L.
Second Advisor
Chao, Mike
Third Advisor
Orwin, Paul
Abstract
The focus of this thesis research was to clarify the role of host Nxf1 in influenza viral mRNA nuclear export. This study aims to define the nuclear mRNA export pathways of influenza viral mRNA. If viral mRNAs are discovered to utilize neither known mRNA nuclear export pathway this would indicate the mRNA exports via undefined mRNA nuclear export pathway. This might be an atypical pathway not utilized by many host mRNAs and thus might reveal novel antiviral target. 293T (Human embryonic kidney cells) and A549 (Human lung epithelial) cells were purchased from ATCC American Tissue Culture Collection.
Recommended Citation
Larsen, Sean William, "Cell type difference in influenza a viral mRNA nuclear export" (2013). Theses Digitization Project. 4042.
https://scholarworks.lib.csusb.edu/etd-project/4042
