OSR Journal of Student Research

Article Title

Muscle Strength and Endurance in Individuals with Cystic Fibrosis


More than 30,000 people in the U.S. live with Cystic Fibrosis (CF) that is a known of. CF is a noncontagious medical disease characterized by its inability to maintain a clear air pathway due to the loss of pulmonary function caused by abnormal production of mucus. The objective of this study to review literatures related muscle strength and endurance of individuals with CF. Further, establishing an effective study protocol for the future study. Recent studies examined healthy individuals and CF patients’ muscle strength and endurance by measuring respiratory and peripheral muscle strength, examining other pulmonary function parameters such as FEV1, total lung capacity and airway resistance (Vendrusculo, Heinzmann-Filho, Piva, Marostica, & Donadio, 2016). However, individuals with pseudomonas aeruginosa and reduction of FEV1 show no difference when resembled with healthy subjects. Researchers found that there was not a significant difference in endurance found in individuals with CF and individuals who are healthy. The findings on the various research done on CF seems controversial. Similarities between muscle endurance and strength between healthy individuals and patients with CF are shocking due to how it would be expected that people with CF are weaker in some aspects. However, even people suffering from CF can be physically active and live a much more stable life. More research is needed for a better understanding of inspiratory muscle strength and endurance that could contribute to the development of earlier preventive measures and help in the therapeutic intervention process in CF.

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