Date of Award


Document Type


Degree Name

Master of Science in Psychology



First Advisor

Crawford, Cynthia

Second Advisor

McDougall, Sanders A.

Third Advisor

Chien, Yuchin


The purpose of this study was to determine if Fischer 344 (F344) rats, a strain which naturally shows deficits in social communication during adolescence, could be used as a model of the social communication deficits observed in autism. Thus, the goal was to determine if F344 rats would also show fewer emissions of isolated-induced ultrasonic vocalizations (an early onset form of social interaction) as compared to SD rats. Subjects consisted of 142 F344 rat pups (67 male and 75 female). Subjects were treated according to the "Guide for the Care and Use of Mammals in Neuroscience and Behavioral Research" under a research protocol approved by the Institutional Animal Care and Use Committee of CSUSB.